SBA — Single Best Answer · Review
Question 20
Feto-maternal medicine → Perinatology
Classification
Question
SSBAOptions
Explanation
RCOG advises that the additional risk of miscarriage following amniocentesis or chorionic villus sampling performed by an appropriately trained operator is likely to be below 0.5% in singleton pregnancies. Counselling should distinguish this additional procedure-related risk from the background risk of pregnancy loss. Local units should also audit their own pregnancy-loss rates following invasive diagnostic procedures.
Option Validity
A) A 5% additional miscarriage risk substantially exceeds the estimate in contemporary RCOG guidance.
B) A 3% additional risk is substantially higher than the estimated additional procedure-related risk.
C) A 2% additional risk is higher than the risk quoted for singleton invasive testing.
D) A 1% additional risk is closer to the approximate figure discussed for twin pregnancies, not uncomplicated singleton procedures.
Further Reading
Navaratnam K, Alfirevic Z; Royal College of Obstetricians and Gynaecologists. Amniocentesis and chorionic villus sampling: Green-top Guideline No. 8. BJOG. 2022;129:e1-e15. Akolekar R et al. Procedure-related risk of miscarriage following amniocentesis and chorionic villus sampling: systematic review and meta-analysis. Ultrasound Obstet Gynecol. 2015.