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Question 295

Physiology → Haematology

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UUID 30a0dc67-a909-4b9d-afc7-a5ccb014312b

Classification

Speciality
Obstetrics and Gynaecology
Group
Basic
Title
Physiology
Topic
Haematology
Subtopic 1
Blood
Subtopic 2
Red blood cells
Subtopic 3
Metabolism — Energy production
Question Type
SBA

Question

SSBA
Question Header
A metabolic inhibitor selectively abolishes mitochondrial ATP production. Which circulating formed element would be least directly affected in its energy production?
Question Stem
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Options

A Erythrocyte
B Neutrophil
C Eosinophil
D Monocyte
E Lymphocyte

Explanation

Mature erythrocytes lack mitochondria as well as a nucleus, DNA and Golgi apparatus. Their energy requirements are met through glycolysis; therefore inhibition of mitochondrial ATP production would not directly remove their stated mechanism of energy production.

Option Validity

B) Neutrophils are nucleated white blood cells rather than mature anucleate erythrocytes. assigns glycolytic energy production in the absence of mitochondria to red blood cells.

C) Eosinophils are granulocytic white blood cells with a bilobed nucleus and characteristic cytoplasmic granules. They are not identified as cells lacking mitochondria.

D) Monocytes are large nucleated leucocytes with abundant cytoplasm and later become tissue macrophages. They do not have the organelle-deficient structure described for mature erythrocytes.

E) Lymphocytes are nucleated leucocytes responsible for cellular or humoral immunity. does not describe them as lacking mitochondria.

Further Reading

Saxena. Textbook for MRCOG-1. Physiology - Haematology - Red Blood Cells, p.67.

Source & metrics

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4.00
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Updated
2026-10-06 01:57:35
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