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Question 309

Physiology → Haematology

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Destination eBook
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Classification

Speciality
Obstetrics and Gynaecology
Group
Basic
Title
Physiology
Topic
Haematology
Subtopic 1
Blood coagulation
Subtopic 2
Haemostasis
Subtopic 3
Bleeding time — Platelet and vascular disorders
Question Type
SBA

Question

SSBA
Question Header
A haemostatic abnormality primarily affects platelets or capillary function while the coagulation cascade itself remains intact. Which laboratory measurement is most directly expected to be prolonged?
Question Stem
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Options

A Prothrombin time only
B Activated partial thromboplastin time only
C Bleeding time
D Both PT and APTT necessarily
E Erythrocyte sedimentation rate

Explanation

Bleeding time measures the interval from the onset of oozing until bleeding arrests and depends on platelet function and vascular contraction. It is prolonged in purpura and disorders involving capillaries or platelets.

Option Validity

A) PT assesses the extrinsic and common coagulation pathways rather than primary platelet and vascular haemostasis. An isolated platelet or capillary disorder therefore does not primarily correspond to an abnormal PT.

B) APTT assesses the intrinsic and common coagulation pathways. The stem instead describes the platelet and vascular components assessed by bleeding time.

D) Platelet or capillary abnormalities do not necessarily prolong both PT and APTT. These tests evaluate coagulation pathways rather than the primary haemostatic mechanism described.

E) ESR is a measure of erythrocyte sedimentation and is influenced by cellular and plasma factors. It is not the test used to assess platelet or capillary haemostasis.

Further Reading

Saxena. Textbook for MRCOG-1. Physiology - Haematology - Bleeding Time, p.71.

Source & metrics

Authored Difficulty
5.00
Evaluation Score
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Destination
eBook
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Updated
2026-10-06 01:57:35
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