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Question 346
Physiology → Haematology
Classification
Question
SSBAQuestion Header
A patient develops widespread purpura due to failure of platelet plugging of capillaries.
Question Stem
Which platelet count range is associated with serious bleeding?
Options
A
150–200 × 10^9/L
B
100–150 × 10^9/L
C
60–80 × 10^9/L
D
Below 20–40 × 10^9/L
E
200–400 × 10^9/L
Explanation
Widespread purpura can result from failure of platelet plugging due to a low platelet count or capillary abnormality. A platelet count below 20–40 × 10^9/L is associated with serious bleeding.
Option Validity
A) 150–200 × 10^9/L is well above the platelet range associated with serious bleeding in this context.
B) 100–150 × 10^9/L does not correspond to the stated threshold for serious bleeding.
C) 60–80 × 10^9/L remains above the range identified with serious bleeding.
E) 200–400 × 10^9/L corresponds to the stated normal platelet-count range rather than severe thrombocytopenia.
Further Reading
Saxena. Textbook for MRCOG-1. Physiology - Haematology - Bleeding Time, p.71.