SBA — Single Best Answer · Review
Question 416
Pathology → General
Classification
Question
SSBAQuestion Header
Which description best defines atrophy?
Question Stem
Select the single best answer.
Options
A
Replacement of one mature differentiated cell type by another
B
Increase in cell size without an increase in cell number
C
Reduction in both the size and number of parenchymal cells in a previously normally developed organ
D
Increase in the number of cells following recruitment from G0
E
Disorderly cellular maturation with loss of polarity
Explanation
Atrophy is characterised by reduction in the size and number of parenchymal cells in an organ that was previously normally developed.
Option Validity
A) This defines metaplasia.
B) This defines hypertrophy.
D) This describes hyperplasia.
E) This describes dysplasia.
Further Reading
Saxena R. Textbook for MRCOG-1. Chapter 5: Pathology. General Pathology, pp.161–175.