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Question 44

Feto-maternal medicine → Maturity

NextGen Workflow Status Needs Review
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Destination eBook
Type SSBA
UUID a750f50d-4669-4c78-8453-c8fa414b6c69

Classification

Speciality
Obstetrics and Gynaecology
Group
Clinical
Title
Feto-maternal medicine
Topic
Maturity
Subtopic 1
Related issue
Subtopic 2
Steroid
Subtopic 3
Multiple pregnancy
Question Type
SBA

Question

SSBA
Question Header
A woman with an uncomplicated dichorionic diamniotic twin pregnancy presents at 31+6 weeks with established preterm labour and progressive cervical dilatation. She has not previously received antenatal corticosteroids.

What is the most appropriate management?
Question Stem
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Options

A Withhold corticosteroids because evidence from singleton pregnancies cannot be applied to twins
B Give corticosteroids only to women with monochorionic twins
C Give two routine courses because this is a twin pregnancy
D Offer a targeted course of antenatal corticosteroids because preterm birth is anticipated
E Wait until one fetus demonstrates evidence of pulmonary immaturity

Explanation

Women with twin or triplet pregnancies should receive targeted antenatal corticosteroids when they meet the same clinical criteria used for singleton pregnancies. Multiple pregnancy alone is not an indication for routine or untargeted corticosteroid administration, but established preterm labour at 31+6 weeks creates a clear risk of imminent preterm birth. This woman therefore falls within the gestational range in which antenatal corticosteroids should be offered. The purpose is to reduce neonatal morbidity associated with prematurity, and the treatment decision should be based on the risk and timing of preterm birth rather than chorionicity or evidence from fetal lung maturity testing. Routine additional courses should not be given simply because two fetuses are present. The appropriate strategy is a targeted course when preterm birth is anticipated. This applies the general recommendations for antenatal corticosteroid use to women with multiple pregnancy while avoiding unnecessary exposure in women who are not genuinely at increased risk of imminent delivery.

Option Validity

A) Targeted antenatal corticosteroid treatment is recommended in multiple pregnancy when the usual criteria for anticipated preterm birth are met.

C) Multiple pregnancy is not an indication for routine additional or untargeted corticosteroid courses.

B) Corticosteroid eligibility is not restricted to monochorionic twin pregnancy.

E) Fetal lung maturity testing is not required before treatment when imminent preterm birth is anticipated.

Further Reading

Stock SJ, Thomson AJ, Papworth S, on behalf of the Royal College of Obstetricians and Gynaecologists. Antenatal corticosteroids to reduce neonatal morbidity and mortality. BJOG. 2022;129:e35–e60. RCOG Green-top Guideline No. 74. doi:10.1111/1471-0528.17027.

Source & metrics

Authored Difficulty
4.00
Evaluation Score
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Destination
eBook
Source
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Source Section
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Updated
2026-10-06 01:57:35
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