SBA — Single Best Answer · Review
Question 464
Pharmacology → General
Classification
Question
SSBAQuestion Header
Which pairing correctly matches a drug associated with hyperglycaemia and a drug associated with hypoglycaemia?
Question Stem
Select the single best answer.
Options
A
Aspirin — hyperglycaemia; glucagon — hypoglycaemia
B
Gliclazide — hyperglycaemia; corticosteroids — hypoglycaemia
C
Thiazide diuretics — hyperglycaemia; ethanol — hypoglycaemia
D
Atenolol — hyperglycaemia; glucagon — hypoglycaemia
E
Ethanol — hyperglycaemia; thiazide diuretics — hypoglycaemia
Explanation
Corticosteroids, thiazide diuretics and glucagon are associated with hyperglycaemia, whereas ethanol, aspirin, gliclazide and atenolol are associated with hypoglycaemia. Therefore, thiazide diuretics paired with ethanol is the correctly oriented combination.
Option Validity
A) Aspirin is associated with hypoglycaemia and glucagon with hyperglycaemia, so both assignments are reversed.
B) Gliclazide is associated with hypoglycaemia and corticosteroids with hyperglycaemia.
D) Atenolol is associated with hypoglycaemia, whereas glucagon is associated with hyperglycaemia.
E) Ethanol is associated with hypoglycaemia and thiazide diuretics with hyperglycaemia, so the assignments are reversed.
Further Reading
Saxena R. Textbook for MRCOG-1. Chapter 12: Pharmacology. Drugs Interfering with Glucose Metabolism, p.347.