SBA — Single Best Answer · Review
Question 485
Pharmacology → General
Classification
Question
SSBAQuestion Header
Which pairing correctly identifies an osmotic diuretic and a characteristic pharmacological effect or use?
Question Stem
Select the single best answer.
Options
A
Metolazone — blood-volume expansion in cerebral oedema
B
Amiloride — blood-volume expansion in cerebral oedema
C
Furosemide — osmotic blood-volume expansion
D
Bendroflumethiazide — osmotic blood-volume expansion
E
Mannitol — blood-volume expansion with use in cerebral oedema
Explanation
Mannitol and urea are osmotic diuretics. They act by expanding blood volume and may be useful in cerebral oedema.
Option Validity
A) Metolazone is a thiazide diuretic rather than an osmotic diuretic.
B) Amiloride is a potassium-sparing epithelial sodium-channel inhibitor rather than an osmotic diuretic.
C) Furosemide is a high-ceiling loop diuretic rather than an osmotic diuretic.
D) Bendroflumethiazide is a thiazide diuretic rather than an osmotic diuretic.
Further Reading
Saxena R. Textbook for MRCOG-1. Chapter 12: Pharmacology. Diuretics, pp.347–348.