SBA — Single Best Answer · Review
Question 496
Endocrinology → General
Classification
Question
SSBAQuestion Header
A physiological study compares circulating hormone patterns during wakefulness and sleep. Which pair would be expected to increase during sleep?
Question Stem
Select the single best answer.
Options
A
Cortisol and adrenaline
B
Antidiuretic hormone and growth hormone
C
Insulin and cortisol
D
Adrenaline and insulin
E
Cortisol and insulin-like growth factor
Explanation
During sleep, antidiuretic hormone and growth hormone increase, whereas cortisol, insulin and adrenaline fall. Growth hormone secretion during sleep contributes to growth and anabolic repair.
Option Validity
A) Cortisol and adrenaline fall during sleep.
C) Both insulin and cortisol fall during sleep.
D) Both adrenaline and insulin fall during sleep.
E) Cortisol falls during sleep; this is therefore not the expected pair.
Further Reading
Saxena, MRCOG-1 Basic Sciences, Endocrinology: Diurnal Variation, p. 300.