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Question 529
Biochemistry → General
Classification
Question
SSBAQuestion Header
A newly synthesised protein enters the Golgi apparatus for processing and subsequent delivery. Which directional sequence through the Golgi is correct?
Question Stem
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Options
A
Trans face → cis face → endoplasmic reticulum
B
Trans face → cis face → cell membrane
C
Endoplasmic reticulum → trans face → cis face
D
Endoplasmic reticulum → cis face → trans face
E
Cell membrane → trans face → cis face
Explanation
The Golgi apparatus receives material from the endoplasmic reticulum at its cis face. Material is processed, packaged and labelled as it passes through the Golgi and leaves from the trans face for delivery.
Option Validity
A) Golgi trafficking does not normally proceed from the trans face back through the cis face to the endoplasmic reticulum.
B) Material enters rather than leaves the Golgi at the cis face.
C) Material from the endoplasmic reticulum enters the cis face before reaching the trans face.
E) The stated pathway reverses the normal direction of Golgi processing.
Further Reading
Richa Saxena. Textbook for MRCOG-1: Basic Sciences in Obstetrics & Gynaecology. Biochemistry and Nutrition — Biochemistry — Golgi apparatus. Printed pages 125–126.