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Question 561
Biochemistry → General
Classification
Question
SSBAQuestion Header
A nuclear structure contains RNA and proteins similar to those found in ribosomes. Dysfunction of this structure would most directly affect which nuclear function?
Question Stem
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Options
A
Beta-oxidation of fatty acids
B
Formation of ribosomal subunits
C
Storage of calcium
D
Lysosomal enzyme activation
E
Chromosome movement by the mitotic spindle
Explanation
The nucleolus is a small, round granular nuclear structure containing RNA and proteins similar to those in ribosomes. The nucleus participates in RNA synthesis and formation of ribosomal subunits; nuclear RNA is described as a precursor of cytoplasmic ribosomal RNA.
Option Validity
A) Fatty-acid beta-oxidation is a principal peroxisomal function.
C) Calcium storage and metabolism are functions of smooth ER.
D) Lysosomal enzymes become active following formation of the acidic secondary lysosome.
E) Chromosome movement during cell division is associated with centrioles and the mitotic spindle.
Further Reading
Saxena R. Textbook for MRCOG-1: Basic Sciences in Obstetrics & Gynaecology. Chapter 4 — Nucleus. Printed page 127.