SBA — Single Best Answer · Review
Question 612
Immunology → General
Classification
Question
SSBAQuestion Header
A lymphocyte forms EAC rosettes and expresses the receptor also used by Epstein-Barr virus. Which receptor accounts for these findings?
Question Stem
Select the single best answer.
Options
A
CD2
B
CR2
C
CD3
D
CD16
E
CD68
Explanation
B lymphocytes bind antibody- and complement-coated erythrocytes to form EAC rosettes because they possess the C3 receptor CR2. CR2 is also the receptor for Epstein-Barr virus.
Option Validity
A) CD2 is associated with T-cell binding to sheep erythrocytes and E-rosette formation.
C) CD3 is associated with the T-cell antigen receptor complex.
D) CD16 is expressed by natural killer cells and participates in responses to antibody-coated cells.
E) CD68 is associated with macrophages.
Further Reading
Saxena MRCOG-1 Basic Sciences — Immunology: B lymphocytes, printed pages 210-211.