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Question 619
Immunology → General
Classification
Question
SSBAQuestion Header
Formation of E rosettes with sheep red blood cells is a characteristic property of T lymphocytes. Which surface molecule mediates this interaction?
Question Stem
Select the single best answer.
Options
A
CD19
B
CR2
C
CD68
D
CD2
E
CD66
Explanation
T lymphocytes possess CD2, which mediates rosette formation with sheep red blood cells. CD2 is also described as a receptor for measles virus.
Option Validity
A) CD19 is a B-lymphocyte marker.
B) CR2 is expressed on B lymphocytes and participates in EAC rosette formation.
C) CD68 is associated with macrophages.
E) CD66 is associated with granulocytes.
Further Reading
Saxena MRCOG-1 Basic Sciences — Immunology: Cells and Humoral Elements of Acquired Immunity, printed pages 209-210.