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EMQ

EMQ — Extended Matching Question · Review

Question 36

Feto-maternal medicine → Perinatology

NextGen Workflow Status Needs Review
SQL status generated
Destination Site
Type EEMQ
UUID 16ed0be8-482a-4e5c-9844-923d4f983c6d

Classification

Speciality
Obstetrics and Gynaecology
Group
Clinical
Title
Feto-maternal medicine
Topic
Perinatology
Subtopic 1
Diagnosis
Subtopic 2
Invasive
Subtopic 3
Blood-borne viruses
Question Type
EMQ

Question

EEMQ
Question Header
Which of the following is the most relevant factor to review?
Question Stem
A pregnant woman with chronic hepatitis B is considering invasive prenatal diagnosis. She asks which maternal factor is particularly important when counselling her regarding vertical transmission risk.

Answer Bank

A Maternal age
B Maternal parity
C Fetal sex
D Placental location
E Previous mode of delivery
F Maternal body mass index
G Number of previous pregnancies
H Maternal hepatitis B viral load

Correct Answer

H) Maternal hepatitis B viral load

Explanation

Maternal hepatitis B viral load is an important determinant when counselling about mother-to-child transmission in the context of invasive prenatal diagnosis. Transmission risk is low when the maternal viral load is below approximately 6.99 log10 copies/mL and increases at higher viral loads. Therefore the woman's blood-borne virus results, including viral load where relevant, should be reviewed and management individualised. Factors such as maternal parity, fetal sex, placental location and body mass index are not the principal viral determinant for this counselling decision.

Option Validity

A) Maternal age is not the principal hepatitis B transmission determinant described here.

B) Parity does not provide the relevant measure of hepatitis B infectivity.

C) Fetal sex is not the key determinant of hepatitis B vertical transmission risk.

D) Placental location is not the principal viral risk measure.

E) Previous mode of delivery does not quantify current hepatitis B infectivity.

F) Maternal body mass index is not the relevant viral transmission marker.

G) Number of previous pregnancies does not quantify hepatitis B transmission risk.

Further Reading

Navaratnam K, Alfirevic Z; Royal College of Obstetricians and Gynaecologists. Amniocentesis and chorionic villus sampling: Green-top Guideline No. 8. BJOG 2022;129:e1-e15. doi:10.1111/1471-0528.16821.

Source & metrics

Authored Difficulty
4.00
Evaluation Score
9.50
Destination
Site
Source
Amniocentesis and chorionic villus sampling: Green-top Guideline No. 8
Source Section
Timing of amniocentesis and chorionic villus sampling
Source Locator
RCOG Green-top Guideline No. 8, October 2021
Updated
2026-10-06 01:57:35
Difficulty Factor
Not available yet
Attended Users
No candidate-attempt data yet
Review Question