SBA — Single Best Answer · Review
Question 37
Feto-maternal medicine → Perinatology
Classification
Question
SSBAOptions
Explanation
Anti-D prophylaxis should be provided to an RhD-negative woman carrying an RhD-positive fetus when she undergoes an invasive prenatal diagnostic procedure. RCOG includes this as an explicit audit standard, with a target of 100% administration in eligible women undergoing invasive procedures. The indication therefore arises from the invasive procedure itself and should not be deferred until subsequent vaginal bleeding occurs.
Option Validity
A) An uncomplicated procedure does not remove the indication for anti-D prophylaxis in an eligible RhD-negative woman.
C) Routine broad-spectrum antibiotic prophylaxis is not the RCOG audit requirement described for an uncomplicated invasive procedure.
D) Routine corticosteroid administration is not indicated solely because an invasive prenatal diagnostic procedure has been performed.
E) Anti-D prophylaxis should follow the invasive procedure in an eligible woman and should not be withheld until vaginal bleeding occurs.
Further Reading
Navaratnam K, Alfirevic Z; Royal College of Obstetricians and Gynaecologists. Amniocentesis and chorionic villus sampling: Green-top Guideline No. 8. BJOG. 2022;129:e1-e15.