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Question 410
Pathology → General
Classification
Question
SSBAQuestion Header
A thrombus removed from a flowing vessel shows alternating pale and dark laminations on sectioning. Which finding best identifies this structure as a thrombus formed in flowing blood?
Question Stem
Select the single best answer.
Options
A
Central caseation
B
Langhans giant cells
C
Lines of Zahn
D
Apoptotic bodies
E
Granulation tissue
Explanation
Lines of Zahn are alternating laminations within a thrombus, with pale platelet-rich layers alternating with darker red-cell-rich layers. Their presence reflects thrombus formation in flowing blood.
Option Validity
A) Central caseation is associated with caseous necrosis and tuberculous granulomas.
B) Langhans giant cells are associated particularly with tuberculous granulomatous inflammation.
D) Apoptotic bodies are produced during programmed cell death.
E) Granulation tissue is part of wound repair and may participate later in thrombus organisation, but it does not describe the characteristic laminations.
Further Reading
Saxena R. Textbook for MRCOG-1. Chapter 5: Pathology. General Pathology, pp.161–175.