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Question 420
Pathology → General
Classification
Question
SSBAQuestion Header
A thrombus persists rather than undergoing complete fibrinolysis. Fibroblasts and vascular elements subsequently grow into it and incorporate it into the vessel wall. Which fate of a thrombus is being described?
Question Stem
Select the single best answer.
Options
A
Propagation
B
Thromboembolism
C
Organisation
D
Resolution
E
Acute liquefaction
Explanation
Recognised outcomes of thrombosis include resolution by fibrinolysis, organisation, propagation and thromboembolism. Ingrowth and incorporation of a persistent thrombus into the vessel wall represents organisation.
Option Validity
A) Propagation refers to extension of the thrombus rather than its incorporation into the vessel wall.
B) Thromboembolism requires detachment and transport of thrombotic material to another vascular site.
D) Resolution involves removal of the thrombus through fibrinolysis rather than persistent structural incorporation.
E) Acute liquefaction is not listed as the relevant fate of a thrombus.
Further Reading
Saxena R. Textbook for MRCOG-1. Chapter 5: Pathology. General Pathology, pp.161–175.