SBA — Single Best Answer · Review
Question 431
Pathology → General
Classification
Question
SSBAQuestion Header
Which form of cell death characteristically provokes an inflammatory response in the surrounding tissue?
Question Stem
Select the single best answer.
Options
A
Apoptosis
B
Necrosis
C
Physiological endometrial shedding
D
Programmed cell deletion
E
Apoptotic-body formation
Explanation
Necrosis is irreversible local cell death associated with injury and hydrolytic degradation and characteristically produces inflammation. Apoptosis is programmed cell death without the associated inflammatory response.
Option Validity
A) Apoptosis characteristically occurs without surrounding inflammation.
C) Physiological endometrial shedding is cited as an example involving apoptosis.
D) Programmed cell deletion describes apoptosis rather than inflammatory necrosis.
E) Apoptotic bodies are characteristic of apoptosis and do not define inflammatory necrosis.
Further Reading
Saxena R. Textbook for MRCOG-1. Chapter 5: Pathology. General Pathology, pp.161–175.