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Question 519
Biochemistry → General
Classification
Question
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A membrane-bound cytoplasmic organelle originates from the endoplasmic reticulum and participates in β-oxidation of excess fatty acids. Which additional function is associated with the same organelle?
Question Stem
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Options
A
Formation of the mitotic spindle
B
Detoxification of hydrogen peroxide
C
Processing and packaging proteins received at the cis face
D
Synthesis of proteins for secretion
E
Formation of ribosomal subunits
Explanation
Peroxisomes are membrane-bound organelles that arise from the endoplasmic reticulum. Their functions include β-oxidation of excess fatty acids and detoxification of hydrogen peroxide. They also participate in oxygen utilisation, gluconeogenesis, degradation of purines to uric acid, and formation of myelin and bile acids.
Option Validity
A) Formation of the mitotic spindle is associated with centrioles.
C) Processing and packaging material entering the cis face are Golgi functions.
D) Protein synthesis for secretion is associated with rough endoplasmic reticulum.
E) Formation of ribosomal subunits is a nuclear function.
Further Reading
Richa Saxena. Textbook for MRCOG-1: Basic Sciences in Obstetrics & Gynaecology. Biochemistry and Nutrition — Biochemistry — Peroxisomes. Printed pages 125–126.