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Question 520
Biochemistry → General
Classification
Question
SSBAQuestion Header
Selective damage to the cristae of a mitochondrion would most directly impair which cellular process?
Question Stem
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Options
A
Processing and labelling of proteins
B
Intracellular digestion by acid hydrolases
C
ATP synthesis by oxidative phosphorylation
D
Formation of ribosomal subunits
E
Steroid synthesis in smooth endoplasmic reticulum
Explanation
The mitochondrial inner membrane is folded to form cristae. The cristae contain the respiratory chain responsible for ATP synthesis by oxidative phosphorylation. Selective damage to the cristae would therefore directly impair this process.
Option Validity
A) Processing and labelling of proteins are functions of the Golgi apparatus.
B) Intracellular digestion by acid hydrolases occurs in lysosomes.
D) Ribosomal subunits are formed within the nucleus.
E) Steroid synthesis is associated with smooth endoplasmic reticulum.
Further Reading
Richa Saxena. Textbook for MRCOG-1: Basic Sciences in Obstetrics & Gynaecology. Biochemistry and Nutrition — Biochemistry — Mitochondria. Printed pages 126–127.