SBA — Single Best Answer · Review
Question 542
Biochemistry → General
Classification
Question
SSBAQuestion Header
Which enzyme is specifically associated with the outer mitochondrial membrane rather than the cristae or mitochondrial matrix?
Question Stem
—
Options
A
Acetyl-CoA synthetase
B
Respiratory-chain enzyme
C
ATP-generating oxidative-phosphorylation component
D
Acid hydrolase
E
Peroxisomal beta-oxidation enzyme
Explanation
The smooth outer mitochondrial membrane is described as containing enzymes including acetyl-CoA synthetase and glycerophosphate acetyltransferase. The respiratory chain and oxidative phosphorylation are associated with the inner membrane and its cristae.
Option Validity
B) Respiratory-chain components are associated with mitochondrial cristae.
C) Oxidative phosphorylation is associated with the inner mitochondrial membrane and cristae.
D) Acid hydrolases characterise lysosomes.
E) Peroxisomal beta-oxidation belongs to peroxisomes rather than the mitochondrial outer membrane.
Further Reading
Saxena - MRCOG-1 Basic Sciences - Biochemistry, printed pp.126–127.