SBA — Single Best Answer · Review
Question 622
Immunology → General
Classification
Question
SSBAQuestion Header
Which granulocyte is particularly associated with defence against large parasites as well as allergic reactions?
Question Stem
Select the single best answer.
Options
A
Neutrophil
B
Basophil
C
Eosinophil
D
Monocyte
E
Macrophage
Explanation
Eosinophils have an important role against large parasites and are also associated with allergic reactions and antigen-antibody complexes. Neutrophils are particularly important in acute inflammation and phagocytosis.
Option Validity
A) Neutrophils are prominent in acute inflammation and are phagocytic, but the stated combination is characteristic of eosinophils.
B) Basophils are not identified as the principal granulocytes involved in defence against large parasites.
D) Monocytes are circulating phagocytes that can differentiate into tissue macrophages.
E) Macrophages are tissue phagocytes rather than granulocytes.
Further Reading
Saxena MRCOG-1 Basic Sciences — Immunology: Phagocytic cells, printed page 211.