SBA — Single Best Answer · Review
Question 623
Immunology → General
Classification
Question
SSBAQuestion Header
Which combination best characterises a dendritic antigen-presenting cell?
Question Stem
Select the single best answer.
Options
A
Surface immunoglobulin positive and CD19 positive
B
CD3 positive and E-rosette forming
C
CD16/CD56 positive with spontaneous cytotoxicity
D
Fc receptor positive with surface immunoglobulin
E
MHC class II positive without Fc receptor, sheep red-cell receptor or surface immunoglobulin
Explanation
Dendritic cells are antigen-presenting cells expressing MHC class II. They lack Fc receptors, sheep red-cell receptors and surface immunoglobulin.
Option Validity
A) Surface immunoglobulin and CD19 are associated with B lymphocytes.
B) CD3 and E-rosette formation are characteristic of T lymphocytes.
C) CD16/CD56 expression with spontaneous cytotoxicity characterises natural killer cells.
D) Dendritic cells are described as lacking Fc receptors and surface immunoglobulin.
Further Reading
Saxena MRCOG-1 Basic Sciences — Immunology: Dendritic cells, printed page 211.